Conversion Between Osmolality and Osmolarity of Infusion Solutions

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Conversion Between Osmolality and Osmolarity of Infusion Solutions

In order to be applied into the body, intravenous fluids should be formulated to have an osmotic pressure similar to that of biological fluids. Physiologic acceptability of large-volume parenteral formulations in clinical practice is largely determined due to the osmotic effect of the dissolved solutes. Therefore, it is generally recommended that the labelling should list osmolarity. However, t...

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Paradoxical effects (bronchoconstriction instead of bronchodilatation) have been reported after inhalation of beta2-mimetics in asthmatic children, and it has been suggested that this was due to osmolality and pH changes of the nebulizer solution. We tested commercially available nebulizer solutions and found osmolality changes after 5, 10 and 15 min of nebulization. Osmolality was measured in ...

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ژورنال

عنوان ژورنال: Scientia Pharmaceutica

سال: 2009

ISSN: 0036-8709,2218-0532

DOI: 10.3797/scipharm.0810-16